Bacteroidales_[G-2] bacterium_HMT_274
(HMT-274)
Taxon Description:
Bacteroidetes bacterium Oral taxon 274 strain F0058 has been isolated from a human subject by the Moore's Laboratory in November 1984. The subject was a 39 year old American black male. The bacteria was isolated from the subgingival oral biofilm at a site with moderate periodontitis. The bacteria was grown in anaerobic conditions. The partial 16S ribosomal RNA gene was deposited to GenBank under the reference FJ577256. The strain is available at www.bei.org under the reference HM-4. This strain is part of the reference strains for the oral section of the Human Microbiome Project.
Disease Associations:
Present in 20% of subgingival sites in healthy subjects and 76% of subgingival sites in periodontitis subjects with a prevalence ratio of 3.85 This disease association is higher thatn that of T. denticola P. gingivalis or T. forsythensis [2]
Prevalence and Source:
26 clones found in libraries from 7 subjectsPresent in 20% of subgingival sites in healthy subjects and 76% of subgingival sites in periodontitis subjects with a prevalence ratio of 3.85 This disease association is higher than that of T. denticola P. gingivalis or T. forsythensis [2]
Bacteroidetes bacterium Oral taxon 274 strain F0058 has been isolated from a human subject by the Moore's Laboratory in November 1984. The subject was a 39 year old American black male. The bacteria was isolated from the subgingival oral biofilm at a site with moderate periodontitis. The bacteria was grown in anaerobic conditions. The partial 16S ribosomal RNA gene was deposited to GenBank under the reference FJ577256. The strain is available at www.bei.org under the reference HM-4. This strain is part of the reference strains for the oral section of the Human Microbiome Project.
Disease Associations:
Present in 20% of subgingival sites in healthy subjects and 76% of subgingival sites in periodontitis subjects with a prevalence ratio of 3.85 This disease association is higher thatn that of T. denticola P. gingivalis or T. forsythensis [2]
Prevalence and Source:
26 clones found in libraries from 7 subjectsPresent in 20% of subgingival sites in healthy subjects and 76% of subgingival sites in periodontitis subjects with a prevalence ratio of 3.85 This disease association is higher than that of T. denticola P. gingivalis or T. forsythensis [2]
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References:
[1] Li CL, Liang JP, Jiang YT. Association of uncultivated oral phylotypes AU126 and X112 with periodontitis. Oral Dis. 2006 Jul;12(4):371-4
[2] Paster BJ, Boches SK, Galvin JL, Ericson RE, Lau CN, Levanos VA, Sahasrabudhe A, Dewhirst FE. Bacterial diversity in human subgingival plaque. J Bacteriol. 2001 Jun;183(12):3770-83
[3] Kumar PS, Griffen AL, Barton JA, Paster BJ, Moeschberger ML, Leys EJ. New bacterial species associated with chronic periodontitis. J Dent Res. 2003 May;82(5):338-44
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