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16S rRNA RefSeq: V15.22    Genomic RefSeq: V9.15
Genus: Rothia
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No Notes
percent abundance
SubPSupPKGBMHPSVTHPTTDST
Avg3.6755.4440.2772.2772.2231.0011.0730.8192.2430.002
Stdev5.1486.8140.7723.8582.7491.5811.4941.2393.0640.012
No Notes
percent abundance
SubPSupPKGBMHPSVTHPTTDST
Avg7.3939.8510.7283.8524.0102.3302.6691.9214.9310.003
10thp0.6071.1330.0000.2450.7620.1710.1500.1410.6900.000
90thp16.36123.4712.2439.0647.4935.3457.0685.11412.9780.000
Stdev8.2259.3431.4105.1783.7223.5142.8842.3845.0860.010
Prev96.10497.40380.51998.70198.70196.10494.80597.403100.0007.792
No Notes
percent abundance
SubPSupPKGBMHPSVTHPTTDST
Avg2.2993.7080.1951.2031.1620.6800.5160.4601.3310.001
10thp0.0710.3040.0000.0260.0280.0530.0000.0000.0000.000
90thp5.3778.6490.3682.8622.8751.6841.3351.0343.5350.000
Stdev3.8185.3680.6802.3651.6080.9640.7170.7072.0870.003
Prev93.91998.64950.67691.21693.24394.59582.43281.08183.7842.797
From: Dewhirst 35x9 data (not published yet)
No Notes
percent abundance
SubPSupPKGBMHPSVTHPTTDNS
Avg5.2993.3600.7744.5113.8813.0541.0470.8511.6100.003
10thp0.0840.2290.0330.4500.4720.2660.1050.0730.0600.000
90thp15.7566.5171.87811.5868.5887.7782.5381.6314.2430.013
Stdev8.1215.9201.5255.5025.5983.2551.0171.3392.1390.007
Prev100.000100.000100.000100.000100.000100.000100.00096.774100.00020.000
Overview: Bacteria of the genus Rothia are abundant in the healthy oral microbiome, making up 3-10% of the bacteria in dental plaque and 1-5% of the bacteria at sites such as the tongue dorsum and buccal mucosa.

Ecological role/importance in health and disease: Three species of genus Rothia are abundant in the oral cavity: R. aeria, R. dentocariosa, and R. mucilaginosa. R. aeria and R. dentocariosa are found predominantly in dental plaque. R. mucilaginosa is abundant on the tongue, where it forms large patches (Wilbert et al. 2020). All three species are capable of nitrate reduction to nitrite and therefore may participate in human nitric oxide homeostasis (Hezel and Weitzberg 2015, Rosier et al. 2020). They can also act as opportunistic pathogens.