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Taxonomy: V4.0   |  16S rRNA RefSeq: V16.01   |  Genomic RefSeq: V11.01
Genus: Haemophilus
Lineage: Bacteria;Pseudomonadota;Gammaproteobacteria;Pasteurellales;Pasteurellaceae;Haemophilus
Overview: Bacteria of the genus Haemophilus are abundant in the mouth, making up several percent of the bacteria at most oral sites (Segata et al. 2012, Eren et al. 2014). Members of the genera Haemophilus and Aggregatibacter are closely related and not always cleanly distinguished using short fragments of the 16S ribosomal RNA gene.

Ecological role/importance in health and disease: Of the twelve species recognized in HOMD, one, H. parainfluenzae, is by far the most abundant at most sites within the mouth. Several others, including H. haemolyticus and an unnamed H. sp. HMT 036, are primarily detected on the keratinized gingiva. The opportunistic pathogen H. influenzae is detected with low prevalence in healthy individuals. Other pathogens such as H. aegyptius and H. ducreyi are included in HOMD as reference strains although they are not generally detected in the healthy oral microbiome. The taxon "Terrahaemophilus aromaticivorans", formerly included in HOMD, is now considered a synonym for H. parainfluenzae.
eHOMD Taxonomy
LifeCellular Organisms
 DomainBacteria (833)HOMD Abundance
  PhylumPseudomonadota (139)HOMD Abundance
   ClassGammaproteobacteria (51)HOMD Abundance
    OrderPasteurellales (18)HOMD Abundance
     FamilyPasteurellaceae (18)HOMD Abundance
      GenusHaemophilus (10)HOMD Abundance
       Species
  •        Haemophilus aegyptius (HMT-535) HOMD Abundance
  •        Haemophilus ducreyi (HMT-821) HOMD Abundance
  •        Haemophilus haemolyticus (HMT-851) HOMD Abundance
  •        Haemophilus influenzae (HMT-641) HOMD Abundance
  •        Haemophilus parahaemolyticus (HMT-945) HOMD Abundance
  •        Haemophilus parainfluenzae (HMT-718) HOMD Abundance
  •        Haemophilus paraphrohaemolyticus (HMT-035) HOMD Abundance
  •        Haemophilus pittmaniae (HMT-946) HOMD Abundance
  •        Haemophilus sp. HMT-036 (HMT-036) HOMD Abundance
  •        Haemophilus sputorum (HMT-944) HOMD Abundance